Main Outcomes and Measures Optical coherence tomography CST and macular volume.
HEIDELBERG OPTICAL COHERENCE TOMOGRAPHY REGISTRATION
Each study eye underwent 2 replicate Stratus scans followed by 2 replicate Cirrus or Spectralis scans (real-time image registration used) centered on the fovea. An additional normative cohort (individuals with diabetes but without diabetic macular edema) was enrolled. Persons with diabetes mellitus who had at least 1 eye with central-involved diabetic macular edema, defined as Stratus central subfield thickness (CST) of 250 μm or greater, participated. Objective To evaluate the reproducibility of retinal thickness measurements from OCT images obtained by time-domain (TD) (Stratus Carl Zeiss Meditec) and spectral-domain (SD) (Cirrus Carl Zeiss Meditec, and Spectralis Heidelberg Engineering) instruments and formulate equations to convert retinal thickness measurements from SD-OCT to equivalent values on TD-OCT.ĭesign, Setting, and Participants A cross-sectional observational study was conducted in private and institutional practices. Importance Understanding measurement variability and relationships between measurements obtained on different optical coherence tomography (OCT) machines is critical for clinical trials and clinical settings. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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